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Question: Answered & Verified by Expert
A mutation at one base of the first codon of a gene forms a non-functional protein. It is called a:
BiologyPrinciples of Inheritance and VariationNEET
Options:
  • A Nonsense mutation
  • B Reverse mutation
  • C Frameshift mutation
  • D Missense mutation
Solution:
2942 Upvotes Verified Answer
The correct answer is: Missense mutation
A point mutation in which a change of a single nucleotide results in a codon for a different amino acid is called a missense mutation. Change in the first base of a codon results in a change in the entire codon as genetic code is degenerate in nature. Due to this, the amino acid changes and so does the nature of the entire protein.

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