A specialized procedure in which an embryo is formed in the laboratory by injecting a sperm directly into the ovum is known as intra-cytoplasmic sperm injection (ICSI). Artificial insemination (AI) is the procedure in which the semen collected from the husband or a healthy donor is inseminated either into the vagina or the uterus. Gamete intra-fallopian tube transfer (GIFT) is a procedure in which the ovum collected from a donor female is transferred into the fallopian tube of a female who is unable to produce an ovum. Zygote intra-fallopian tube transfer (ZIFT) is a procedure in which the zygote or early embryo with up to 8 blastomeres is transferred to the fallopian tube.