Amides are formed by the reaction of acid chloride with

Question

Amides are formed by the reaction of acid chloride with, $ \mathrm{NH}_{2} \mathrm{NH}_{2} $, $ \mathrm{NH}_{3} $, $ \mathrm{NH}_{2} \mathrm{OH} $, $ \mathrm{C}_{6} \mathrm{H}_{5} \mathrm{NHNH}_{2} $

MARKS App · Accepted Answer

It is the acyl substitution reaction. In which Cl atom is replaced by -NH 2 group. Nucleophile ammonia attacks at the electrophilic carbon of acid halide. Addition-elimination reaction takes place and product is amide formed after removal of leaving group HCl RCO - Cl + H - NH 2 → R - CONH 2 + HCl

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