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Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
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Chromosomes will not segregate
Anaphase Promoting Complex (APC) is a protein necessary for the separation of daughter chromosomes during anaphase.
APC degenerates proteins binding the two chromatids in the region of the centromere. As a result, the centromere of each chromosome divides.
If APC is defective, then the chromosomes will fail to segregate during anaphase.
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