Females having 45 chromosomes $(2 \mathrm{~A}+\mathrm{X} 0)$ are affected with Turner's syndrome. Individuals having Turner's syndrome have female sexual differentiation but ovaries are rudimentary. Other associated phenotypes of this condition are short stature, webbed-neck, broad chest, lack of secondary sexual characteristics and sterility. Thus, any imbalance in the copies of the sex chromosomes may disrupt the genetic information necessary for normal sexual development.