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Certain genetic disorders show a higher proportion of males to be affected as compared to females that are affected. Such genetic disorders can arise due to
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Recessive trait carried by X-chromosome
Genetic disorders due to recessive genes present on the X-chromosome are more prevalent in males as compared to females because of the homozygous condition of males. In males, a single recessive able present on X-chromosome can cause the disease, while it requires both the alleles to be recessive in females for the symptoms to be visible.
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