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Question: Answered & Verified by Expert
If a completely radioactive double-stranded DNA molecule undergoes two rounds of replication in a non-radioactive medium, what will be the radioactive status of the four resulting molecules?
BiologyMolecular Basis of InheritanceNEET
Options:
  • A All four still contain radioactivity
  • B Three out four contain radioactivity
  • C Radioactivity is lost from all four
  • D Half the number contain no radioactivity
Solution:
1486 Upvotes Verified Answer
The correct answer is: Half the number contain no radioactivity
DNA replication is semiconservative, i.e., during each replication cycle, one of the parental strands is retained and a new daughter strand is obtained. Thus, only half of the parental DNA molecule is carried to the next generation.

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