If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

Question

If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?, No chance, 50%, 25%, 100%

MARKS App · Accepted Answer

Thalassemia is the disorder due to reduced synthesis of either the α or β -chains, likewise designated as α or β - thalassemias. When this autosomal mutant gene is present in double dose. The disease is severe called as thalassemia major.

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