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Question: Answered & Verified by Expert
In a DNA molecule, nitrogenous base is linked to pentose sugar by 'A' linkage and the pentose sugar is linked to phosphate by 'B' linkage. Correctly identify A and B.
BiologyMolecular Basis of InheritanceNEET
Options:
  • A
    Column A Column B
    N-Glycoside linkage Amide linkage
  • B
    Column A Column B
    N-Glycoside linkage Phosphodiester linkage
  • C
    Column A Column B
    Phosphoester linkage Phosphoester linkage
  • D
    Column A Column B
    Amide linkage Phosphodiester linkage
Solution:
2902 Upvotes Verified Answer
The correct answer is:
Column A Column B
N-Glycoside linkage Phosphodiester linkage
Structure of polynucleotide chain

DNA = Polynucleotide.

Nucleotide = Nitrogenous base + Pentose sugar + Phosphate group.

As nitrogenous base and pentose sugar when linked, are also termed as nucleoside, so we can also say that : Nucleotide = Nucleoside + Phosphate group.

Linkages in a nucleotide molecule:

Nitrogenous base --(N-glycosidic linkage)-- Pentose sugar --(Phosphodiester linkage)-Phosphate group. Phosphate group is linked to 5  OH of a nucleoside through the phosphoester linkage.

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