In the context of the rearrangement of an oxime of a ketone to an amide (represented below) Which of the following statement is/are correct?

Question

In the context of the rearrangement of an oxime of a ketone to an amide (represented below) Which of the following statement is/are correct?, It is the cis hydrocarbon radical $ (R) $ with respect to the $ \mathrm{OH} $ group that migrates, The group that migrates never gets completely detached from the remainder of the molecule during the transformation, The rearrangement is intermolecular, None of the above

MARKS App · Accepted Answer

This reaction is an example of Backmann rearrangement. It is an intramolecular rearrangement. Beckmann Rearrangement is a reaction where oxime is changed to an amide. Beckmann rearrangement consists of an alkyl group migration, that is anti-periplanar to the expulsion of a leaving group and form nitrilium ion. This is followed by attack of water molecule to an imidate and then tautomerization to the amide:

Search any question & find its solution

Looking for more such questions to practice?