Prosthetic groups differ from coenzymes in that

Question

Prosthetic groups differ from coenzymes in that, they require metal ions for their activity, they (prosthetic groups) are tightly bound to apoenzymes, their association with apoenzymes is transient, they can serve as cofactors in a number of enzyme catalysed reactions

MARKS App · Accepted Answer

Prosthetic groups are organic compounds and are distinguished from other cofactors in that they are tightly bound to the apoenzyme. For example, in peroxidase and catalase, which catalyse the breakdown of hydrogen peroxide to water and oxygen, haem is the prosthetic group and it is a part of the active site of the enzyme.

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