Thyroid hormones secreted by thyroid glands are ${\mathrm{T}}_3$ and ${\mathrm{T}}_4.\mathrm{ }{\mathrm{T}}_4$ (thyroxine) is the chief circulating hormone but less active than ${\mathrm{T}}_3$. Thyroxine is responsible for metamorphosis in amphibian as it increases metabolism. Milk ejecting hormone is oxytocin that is produced by paraventricular nuclei of the hypothalamus but stored in the posterior pituitary. Acromegaly is a condition seen due to hypersecretion of growth hormone. Hypersecretion is concerned with hyperglycemia and hypertension too as high levels of growth hormone stimulates gluconeogenesis and lipolysis.