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Question: Answered & Verified by Expert
RNA interference involves:
BiologyBiotechnology and Its ApplicationsNEETNEET 2013 (Karnataka)
Options:
  • A synthesis of $\mathrm{DNA}$ and RNA using reverse transcriptase.
  • B silencing of specific $m \mathrm{RNA}$ due to complementary RNA
  • C interference of RNA in synthesis of DNA
  • D synthesis of mRNA from DNA.
Solution:
2491 Upvotes Verified Answer
The correct answer is: silencing of specific $m \mathrm{RNA}$ due to complementary RNA
The process of RNA interference (RNA $i$ ) involves silencing of a specific $m$ RNA due to a complementary dsRNA molecule that binds to and prevents translation of the $m$ RNA, also referred as RNA silencing.
Related Theory
In RNAi, the source of this complementary $R N A$ could be from an infection by viruses having RNA genomes or transposons. Using Agrobacterium vectors, nematode-specific genes were introduced into the host plant such that it produced both sense and antisense RNA in the host cells. Two RNAs being complementary to each other formed a double stranded RNA (dsRNA) and thus, silenced the specific $m R N A$ of the nematode. The process of RNA interference was adopted to prevent the infection of tobacco plants by Meloidegyne incognita.

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