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Question: Answered & Verified by Expert
The most susceptible compound to nucleophilic attack at the carbonyl carbon among the given bellow group is
ChemistryGeneral Organic ChemistryJEE Main
Options:
  • A MeCOCl
  • B MeCHO
  • C MeCOOMe
  • D MeCOOCOMe
Solution:
2453 Upvotes Verified Answer
The correct answer is: MeCOCl
Amongst aldehyde & the acid derivatives, acid chloride are the most susceptible to nucleophilic attack due to strong -I effect & weak +R effect of the Cl- atom as a result of which carbonyl carbon has the highest electron deficiency. The actual order is

MeCOCl>MeCOOCOMe >MeCOOMe >MeCHO .

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