Drugs that bind to the receptor site and inhibit its natural function are called antagonists. Antagonists are molecules that bind to receptors but do not activate them. Instead, they block the action of other molecules, including natural ligands and agonists, that normally bind to the receptor and activate it. Antagonists inhibit the natural communication of the body by preventing the binding of the natural ligands, which can result in physiological effects such as decreased heart rate, blood pressure, and inflammation.