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Tobacco plants resistant to a nematode have been developed by the introduction of DNA that produced (in the host cells)
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both sense and antisense RNA
Antisense RNA can be produced by inverting a cDNA copy of an mRNA with respect to the promoter in an expression vector. This yields a full length complementary copy of the mRNA sequence. Antisense RNA molecule are thought to interact with mRNA molecule by base pairing to form double stranded RNA.
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