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Write the structures of fragments produced on complete hydrolysis of DNA. How are they linked in DNA molecule? Draw a diagram to show pairing of nucleotide bases in double helix of DNA.
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A pentose sugar ( $\beta$-D-2-deoxyribose), phosphoric acid $\left(\mathrm{H}_3 \mathrm{PO}_4\right)$ and bases (nitrogen containing heterocyclic compounds) 349are produced on complete hydrolysis of DNA.
Their structure is given below:
(i) Pentose sugar

$$
\text { (ii) Phosphoric acid }
$$
(iii) Nitrogen bases There are four bases in DNA. Adenine (A), Guanine (G), Cytosine (C) and Thymine (T).



A unit formed by the attchment of a base to 1 '-position of sugar is called nucleoside. When nucleoside links to phosphoric acid at 5'-position of sugar moiety, a nucleotide is formed. Nucleotides are joined together by phosphodiester linkage between 5 ' and $3^{\prime}$ carbon atoms of the pentose sugar.
In DNA two nucleic acid chains are wound about each other and held together by hydrogen bonds between pairs of bases.
The two strands are complementary to each other because hydrogen bonds are formed between specific pair of base. Adenine of one strand is hydrogen bonded to thymine of the other strand through two hydrogen bonds. Cytosine of one strand is hydrogen bonded with guanine of the other strand through three hydrogen bonds. Double stranded helix structure of DNA is represented as follows:
Their structure is given below:
(i) Pentose sugar

$$
\text { (ii) Phosphoric acid }
$$

(iii) Nitrogen bases There are four bases in DNA. Adenine (A), Guanine (G), Cytosine (C) and Thymine (T).




A unit formed by the attchment of a base to 1 '-position of sugar is called nucleoside. When nucleoside links to phosphoric acid at 5'-position of sugar moiety, a nucleotide is formed. Nucleotides are joined together by phosphodiester linkage between 5 ' and $3^{\prime}$ carbon atoms of the pentose sugar.
In DNA two nucleic acid chains are wound about each other and held together by hydrogen bonds between pairs of bases.
The two strands are complementary to each other because hydrogen bonds are formed between specific pair of base. Adenine of one strand is hydrogen bonded to thymine of the other strand through two hydrogen bonds. Cytosine of one strand is hydrogen bonded with guanine of the other strand through three hydrogen bonds. Double stranded helix structure of DNA is represented as follows:

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