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Question: Answered & Verified by Expert
In 1963, two enzymes responsible for restricting the growth of bacteriophage in E. coli were isolated. They were _____ and _____ respectively.
BiologyBiotechnology - Principles and ProcessesNEET
Options:
  • A Ligase, Restriction endonuclease
  • B Helicase, Restriction endonuclease
  • C Methylase, Restriction endonuclease
  • D DNA polymerase, Restriction endonuclease
Solution:
2770 Upvotes Verified Answer
The correct answer is: Methylase, Restriction endonuclease
The enzyme that restricted the growth of the bacteriophage is called a restriction enzyme. One of the enzymes was methylase which added methyl groups to the adenine base of the DNA thereby restricting or inhibiting the growth of bacteriophage.

Restriction endonuclease is enzymes that cut the DNA at specific sites and eliminating the foreign DNA or infecting organism.

These two groups of restriction enzymes were isolated from E. coli.

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