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NHC structural proteins are
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required for packaging of chromatin at higher levels
The packaging of chromatin at higher level requires additional set of proteins that collectively are referred as Non - histone chromosomal (NHC) proteins. Non - histone chromosomal proteins are of three types :
(i) Scaffold or structural NHC
(ii) Functional NHC protein e.g., DNA polymerase, RNA polymerase
(iii) Regulatory NHC protein e.g., HMG (High mobility group proteins that controls gene expression)
(i) Scaffold or structural NHC
(ii) Functional NHC protein e.g., DNA polymerase, RNA polymerase
(iii) Regulatory NHC protein e.g., HMG (High mobility group proteins that controls gene expression)
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