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The dipeptide, Gln-Gly, on treatment with $\mathrm{CH}_3 \mathrm{COCl}$ followed by aqueous work up gives.
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Amino group of glutamine is acetylated. Amide group of glutamine is not acetylated. Note :
Acetylation of amide requires activation of amides and /or acyl donors, since the nitrogen atom of amides is less basic than that of the corresponding amines due to amide resonance.
Acetylation of amide requires activation of amides and /or acyl donors, since the nitrogen atom of amides is less basic than that of the corresponding amines due to amide resonance.
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